FST-344 · Follistatin
Myostatin inhibitor — significant lean mass increases.
FDA
Research Only
WADA
Banned
HALF-LIFE
~3–4 hours
ROUTE
IM injection
SCHEDULE
Daily or every other day
In Plain English
Myostatin inhibitor — significant lean mass increases.
Status & Legality
What do these mean?Myostatin inhibition
Lean mass gain
Muscle endurance
Strength
Follistatin-344 is a glycoprotein that binds and inhibits myostatin — the primary negative regulator of muscle growth. By blocking myostatin, it removes the genetic 'brakes' on muscle development. Studies show significant increases in muscle mass with minimal fat gain. Highly sought after in performance communities.
Hypoglycemia
Muscle soreness
Potential tumor promotion (theoretical)
Joint discomfort
Headache
Insufficient protein intake — myostatin inhibition creates the opportunity for growth; protein provides the building material; without ≥1.5 g/kg, results are blunted
Running continuously without cycling — 30-day maximum cycles are standard; longer continuous use may impair muscle quality markers
Expecting dramatic changes in weeks — Follistatin cycles produce meaningful results over 4–8 weeks; impatience leads to inappropriate dose escalation
IGF-1 LR3 — synergistic; myostatin blockade + direct IGF-1 receptor stimulation for comprehensive anabolic effect
Anabolic steroids — potent combination; experienced guidance required due to compounded effects
GH secretagogues — additive growth factor signaling; monitor for adverse effects at high doses
Follistatin 344 removes the genetic ceiling on muscle growth by blocking myostatin — the body's primary brake on muscle development. The results are significant and well-documented in the performance community. It sits firmly in the 'advanced' category: potency, limited safety data, and WADA-banned status mean experienced guidance and careful cycling are mandatory.
IGF-1 LR3
Long-acting IGF-1 — muscle growth and satellite cell activation.
CJC-1295 (NO DAC)
Short-acting GHRH analog — clean GH pulses.
IGF-1 DES
Short-acting IGF-1 — localized muscle hypertrophy.
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Stats
Sources & Studies
Kota J. et al., Sci Transl Med, 2009