TA1 · Thymalfasin · Zadaxin
Immune modulator — infection resistance and anti-cancer.
FDA
Compounding Allowed
WADA
Not Listed
HALF-LIFE
~2 hours
ROUTE
SubQ injection
SCHEDULE
2× weekly
In Plain English
Immune modulator — infection resistance and anti-cancer.
Status & Legality
What do these mean?Immune enhancement
Antiviral activity
Cancer adjunct therapy
Hepatitis
Thymosin Alpha-1 (TA1) is the most potent immune-modulating peptide currently available. Approved in 37 countries for hepatitis B and C, it modulates T-cell maturation, enhances NK cell activity, and has shown benefit in cancer immunotherapy. It's used by longevity practitioners for immune optimization and during immune challenges.
Injection site reactions
Flu-like symptoms at start (immune activation)
Generally very well tolerated
Storing improperly — TA1 is heat-sensitive; refrigerate before use and do not leave reconstituted solution at room temperature
Using 0.9 mg when 1.6 mg (the clinically validated dose in 37-country approvals) is available and warranted
Expecting results within days for chronic immune conditions — TA1 builds and restores immune function over weeks of consistent use
Immunosuppressants — directly antagonistic; avoid combination in organ transplant patients on maintenance suppression
Interferon — additive antiviral effects; used in combination clinically for hepatitis B and C
Corticosteroids — may blunt TA1's immune-enhancing effects; avoid combining during active immune restoration protocols
Thymosin Alpha-1 is the most clinically validated immune peptide available — approved in 37 countries for hepatitis B and C with extensive human safety data. At 1.6 mg 2×/week, it reliably improves immune surveillance. For acute illness, daily dosing for 1–2 weeks is the accelerated protocol most longevity practitioners use.
THYMALIN
Thymic longevity peptide — immune restoration and anti-aging.
EPITHALON
Telomere extension peptide — the longevity compound.
THYMULIN
Thymic hormone — T-cell maturation and immune aging.
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Stats
Sources & Studies
Goldstein AL. et al., Expert Opin Biol Ther, 2009