CJC-1295 · DAC:GRF
Long-acting GHRH analog — once or twice weekly dosing.
FDA
Reclassified '26
WADA
Banned
HALF-LIFE
6–8 days
ROUTE
SubQ injection
SCHEDULE
1–2× weekly
In Plain English
Long-acting GHRH analog — once or twice weekly dosing.
Status & Legality
NATTY?
Not NattyWADA banned substance. Tested athletes will fail.
FDA
Reclassified '26Compounding pharmacies may prepare under physician oversight.
WADA
BannedOn WADA prohibited list. Use disqualifies in tested sports.
COMPOUNDING
Category 1Compounding pharmacies may prepare post-2026 reclassification.
PRESCRIBED
Off-label compoundsNot prescribed in conventional medicine.
ROUTE
SubQ injectionAdministration via subq injection.
GH stimulation
Anti-aging
Muscle recovery
CJC-1295 with DAC (Drug Affinity Complex) extends the half-life to 6–8 days by binding to albumin. This creates a sustained GH release (the 'bleed') rather than sharp pulses. Ideal for those wanting convenience — once or twice weekly injections. The trade-off is less physiological pulse rhythm.
Water retention (more than no-DAC version)
Tingling
Fatigue
Hunger
Potential desensitization with long-term continuous use
Using without a GHRP — the sustained bleed without pulsatile release is significantly less effective than the combination
Dosing more than twice weekly — once or twice weekly is sufficient; more frequent dosing creates desensitization without added benefit
Expecting immediate results — sustained GH elevation from DAC takes 2–4 weeks to show measurable effects on body composition
Insulin — GH elevation reduces insulin sensitivity; monitor glucose during extended cycles
Somatostatin analogs (octreotide) — block GH release; do not combine
Thyroid hormones — thyroid optimization before GH axis protocols improves the overall response
CJC-DAC's convenience (1–2 injections/week) is its main selling point. The trade-off is less physiological GH pulsing compared to no-DAC. If you want the cleanest, most natural pulse rhythm, use no-DAC + Ipamorelin. If compliance and convenience matter more than optimization, DAC is a reasonable choice.
Stats
Sources & Studies
Teichman SL. et al., J Clin Endocrinol Metab, 2006