Ala-Glu-Asp · EDG tripeptide
Pineal gland peptide — neuroprotection and biological clock regulation.
FDA
Research Only
WADA
Not Listed
HALF-LIFE
Unknown
ROUTE
SubQ injection or intranasal
SCHEDULE
Daily (10-day cycle)
In Plain English
Pineal gland peptide — neuroprotection and biological clock regulation.
Status & Legality
What do these mean?Neuroprotection
Circadian rhythm
Cognitive aging
Retinal health
Pinealon is a tripeptide (EDG) derived from the pineal gland that regulates biological clock function and provides neuroprotection. Russian research shows it improves circadian rhythms, protects against age-related neurodegeneration, enhances visual acuity, and reduces all-cause mortality when used in longevity protocols.
Mild headache (rare)
Vivid dreams
Generally very well tolerated
Not combining with Epithalon — Pinealon + Epithalon is the standard Russian neuroprotection protocol; running solo misses the complementary mechanisms
Expecting cognitive improvements within days — effects are cumulative over the 10-day cycle and across months of consistent cycling
Injecting IM instead of SubQ or intranasal — the preferred routes for Pinealon are SubQ or intranasal
Melatonin — synergistic for circadian regulation and sleep quality optimization
SSRIs — may interact via serotonin pathway modulation given Pinealon's circadian involvement
No known significant adverse drug interactions
Pinealon is the most overlooked compound in the Russian longevity peptide set. The circadian regulation and retinal health effects are distinctive — no other peptide in the index targets biological clock function this directly. Best used as part of the Epithalon + Thymalin cycle rather than standalone.
EPITHALON
Telomere extension peptide — the longevity compound.
SELANK
Anti-anxiety nootropic — calm focus without sedation.
GHK-CU
Anti-aging copper peptide — skin, hair, collagen, and wound repair.
Free, no account needed
Drop your email and we'll send the one-page starter checklist beginners actually need first. No account needed.
No spam, and we never sell your email. Just the checklist. Email support@pepvault.us to opt out any time.
Stats
Sources & Studies
Pinealon increases cell viability and reduces caspase-3 activity in photoreceptors and retinal pigment epithelium
Khavinson VKh. et al., Neuroendocrinol Lett, 2012